The first step towards the beginnings of understanding anabolic steroids and how they operate is through the thorough understanding of Testosterone itself. Quite literally, all anabolic steroids are synthetic derivatives of Testosterone, or a modification of a derivative of Testosterone. This is to say that Testosterone’s chemical structure is modified in a variety of different ways, and these modifications are what produce a brand new anabolic steroid – but it is regarded as a Testosterone analogue (or derivative). In this case, Testosterone is what is known as the precursor hormone to the derivative. Other descriptive terms also refer to Testosterone as being the parent hormone, or progenitor hormone of the derivative or analogue hormone. Testosterone is endogenously manufactured by the human body in the Leydig cells of the testes. The term ‘endogenous’ refers to the origin of Testosterone from within the body (referring to production within the human body by the body’s own cells), while the term ‘exogenous’ refers to the origin of a substance from outside of the body (through ingestion, injection, etc.). There exist two other endogenously manufactured hormones within humans that are utilized as progenitor hormones to create anabolic steroid derivatives. These are: Nandrolone and Dihydrotestosterone (DHT).
Testosterone is metabolized into Dihydrotestosterone in the body by way of the 5-alpha reductase (5AR) enzyme (this means that Dihydrotestosterone is a metabolite of Testosterone), and furthermore, Nandrolone is a byproduct of the aromatization (conversion) of Testosterone into Estrogen.With this knowledge, it then stands to reason that Testosterone quite literally is the origin of all anabolic steroids. Without Testosterone, DHT and Nandrolone would not even exist, and therefore without the existence of DHT and Nandrolone, their individual derivatives and analogues would also not exist.
Testosterone itself is the principal male sex hormone. Hormones are defined and classified as chemical messengers of the human body, which means that hormones are what send messages to different cells and tissues in the body to tell those cells and tissues what to do (grow muscle tissue, heal and repair, manufacture important components, perform a specific job, etc.). Without hormones of all different types, all functions within the human body will proceed unregulated and out of control. How much Testosterone the average male produces is dependent on many different factors, which include: individual genetics, age, lifestyle habits, nutritional habits, and activity levels. On average, it has been determined that the median level of Testosterone production among males is between 50 – 70mg weekly. Where any given individual might land within that range is dependent on the aforementioned factors. It is common knowledge that the most prominent effects of the hormone Testosterone appear and are experienced during puberty, which is evidenced by an increase in Testosterone production and secretion, and will typically reach the highest endogenous levels at this point in any given man’s life. This significant increase in Testosterone serves to impart very important physiological changes of the male human body. Testosterone governs many different functions within the body, as is typical of nearly all hormones. The nature of hormones is to govern systemic functions all throughout the body, and Testosterone is no exception to this.
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