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|CAS NO.:||189691-06-3||Purity:||99% By HPLC|
|MOQ:||1 Box||Price:||US $40-$80|
|Payment Termsard:||Western Union, MoneyGram, T/T, Bank Transfer And BTC||Supply Ability:||5000 Boxes Per Month|
CAS 189691-06-3 PT141 Bremelanotide,
Sexual Dysfunction Improving PT141 Bremelanotide
Human Growth Hormone Peptides PT141 Bremelanotide for Improve Sexual Dysfunction PT 141
|Other name||PT-141 Acetate. Bremelanotide|
|Package||10 mg/vial, 10 vials/box|
|Storage||Lyophilized peptides although stable at room temperature for 3 months, Should be stored desiccated below -18°C.Upon reconstitution of the peptids.
It should be stored at 4°C between 2-21 days and for future use below -18°C.
PT-141 or Bremelanotide is the generic term for a research peptide being studied for its possible use in helping to improve sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder). PT-141 was developed from the tanning peptide Melanotan 2, which is a synthetically produced variant of a peptide hormone naturally produced in the body that stimulates melanogenesis that is known as alpha-Melanocyte stimulating hormone. MSH, activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido. Resultantly, PT-141 has been shown in studies to exhibit libido-enhancing effects by activating the melanocortin receptors MC1R and MC4R, but not skin tanning. Melanotan 1 and Melanotan 2 have been researched for their use in protecting against the harmful effects of ultraviolet radiation from sunlight due to their melanogenesis-stimulating properties.
As a lifestyle peptide, the 10mg product is a lot to consume and may offer up to 20 doses when dosing light. The PT-141 peptide reconstituted with bacteriostatic water remains potent in the fridge for months.
PT-141 / Bremelanotide is a synthetic heptapeptide analogue of the naturally occuring α-MSH that is currently being studied for its numerous theoretical therapeutic applications. Alpha-MSH has potent influence over lipid metabolism, appetite, and sexual libido.
PT-141/ Bremelanotide is a metabolite of its predecessor MT-2, has the amino acid sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH and a molecular weight of 1025.2 Dalton.
In initial testing, MT-2 did induce melanogenesis, but caused sexual arousal and spontaneous erections as unexpected side effects in nine out of the ten original male volunteer test subjects Alpha-MSH activates certain melanocortin receptors in the process of exerting its effects.
PT-141 is a potential remedy for the treatment of sexual dysfunction; specifically, male erectile dysfunction. Studies have shown that PT-141 does not act on the vascular system like former compounds, but allegedly works by activating melanocortin receptors in the brain, therefore helping increase ones sexual stimulation. PT-141 is a melanocortin based peptide that has shown effectiveness in clinical studies on both male and female rats. Male rats have shown erectile response with doses as low as 1-2 mgs whereas most female rats have shown positive results with higher doses around 2-3 mgs. While the dosage requirements tend to be higher for female rats, the observable results in female rats tend to be stronger.
|Items of analysis||Specification||Results|
|Appearance||White to almost white crystalline hygroscopic powder||White powder|
|Identification||A: IR absorption B: Thin-layer chromatographic identification test||Conforms|
|Loss of drying||Should conform to the standard||Conform|
|Melting range||NMT 1.0%||0.35%|
|Heavy metals||164 ºC -168 ºC||165.4-166.5ºC|
|Acidity or alkalinity:||NMT 20ppm||<20ppm|
|Residue on ignition||NMT 0.1%||0.05%|
|Chromatographic||Total impurities: NMT2.0%||Conforms|
|Solution clarity||Meet the requirement(CP Standard)||Conforms|
|Assay||Not less than 98.0% and not more than 102.0%||99.47%|
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